Lithocholic acid

• Target :

  Endogenous Metabolite|||Autophagy|||Apoptosis|||FXR

• Related Pathways :

  Metabolism|||Apoptosis|||Autophagy

• Purity :

  0.9998

• Bioactivity :

  Lithocholic acid (3?-Hydroxy-5?-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 ?M), EphA2 antagonists (IC50=48, 66 ?M) and EphB4 antagonists (IC50=141 ?M) . Lithocholic acid can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is a cleanser that dissolves fat for absorption and is itself absorbed.

• Smiles :

  [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

• Molecular Formula :

  C24H40O3

• Molecular Weight :

  376.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  434-13-9