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Lithocholic acid

CAT: 0931-T2202-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T2202-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
434-13-9
Target
Endogenous Metabolite, Autophagy, Apoptosis, FXR
Related Pathways
Metabolism, Apoptosis, Autophagy
Purity
0.9998
Bioactivity
Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM), EphA2 antagonists (IC50=48, 66 μM) and EphB4 antagonists (IC50=141 μM) . Lithocholic acid can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is a cleanser that dissolves fat for absorption and is itself absorbed.
Smiles
[H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
Molecular Formula
C24H40O3
Molecular Weight
376.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
A8463-1000Lithocholic Acid

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