Direct Blue 1

• Target:

  NF-?B|||Beta Amyloid|||GluR

• Related Pathways:

  Neuroscience|||NF-?B

• Purity:

  0.9779

• Bioactivity:

  Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit A? binding.

• Smiles:

  COc1c(ccc(c1)c1cc(c(cc1)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]

• Molecular Formula:

  C34H24N6Na4O16S4

• Molecular Weight:

  992.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  259444