Fluconazole hydrate

CAT: 0931-MF-0052309-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0052309-01Size:25 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
155347-36-7
Target
Others|||Antifungal|||Antibacterial|||Antibiotic
Related Pathways
Others|||Microbiology/Virology
Bioactivity
Fluconazole (hydrate) is a triazole antifungal agent used for oral treatment and prevention of both superficial and systemic fungal infections, including but not limited to balanitis, various Candida infections, Cryptococcus infections, dermatomycosis, and fungal infections of the respiratory and urinary tracts. As the hydrate salt form of fluconazole, it exhibits antifungal activity by inhibiting the growth and development of pathogenic fungi, such as Candida species, at minimal inhibitory concentrations often exceeding 100 mg/l. Notably, it disrupts the branching and hyphal formation in C. albicans at concentrations as low as 0.3 mg/l, indicating its potency compared to other antifungals like miconazole and ketoconazole which are effective at 100-fold lower concentrations. Clinical studies have not shown a significant increase in the risk of most birth defects with oral fluconazole, although there may be an associated risk of tetralogy of Fallot. Its efficacy against Cryptococcus gattii in koalas suggests it may be ineffective as a sole therapeutic agent at a dosage of 10 mg/kg orally every 12 h. Toxicity symptoms from overdose can include hallucinations and paranoid behavior.
Smiles
O.OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F
Molecular Formula
C13H14F2N6O2
Molecular Weight
324.292
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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