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INCA-6

CAT: 0931-T21807-06Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0931-T21807-06Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3519-82-2
Target
Others
Related Pathways
Others
Purity
0.9988
Bioactivity
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor that disrupts CN-NFAT signaling by targeting the NFAT (P) substrate at the calcineurin (CN) phosphatase site.
Smiles
O=C1C=CC(=O)C2=C1C1c3ccccc3C2c2ccccc12
Molecular Formula
C20H12O2
Molecular Weight
284.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

9,10-Dihydro-9,10(1',2')-benzenoanthracene-1,4-dione

INCA-6 is a quinone that is 9,10-dihydroanthracene-1,4-dione that is a linked to a benzene ring via 9 and 10 positions. It is an inhibitor of the interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT). It has a role as an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor. It is a quinone and an organic heteropentacyclic compound.

CAS Number3519-82-2
PubChem CID230748
IUPAC Namepentacyclo[6.6.6.02,7.09,14.015,20]icosa-2(7),4,9,11,13,15,17,19-octaene-3,6-dione
Molecular FormulaC20H12O2
Molecular Weight284.3
XLogP3
Topological Polar Surface Area34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Heavy Atom Count22
Formal Charge0
Complexity535
SMILES
C1=CC=C2C3C4=CC=CC=C4C(C2=C1)C5=C3C(=O)C=CC5=O
InChI
InChI=1S/C20H12O2/c21-15-9-10-16(22)20-18-12-6-2-1-5-11(12)17(19(15)20)13-7-3-4-8-14(13)18/h1-10,17-18H
InChIKey
GCHPUOHXXCNSQL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 9,10-Dihydro-9,10(1',2')-benzenoanthracene-1,4-dione
CAS: 3519-82-2
CID: 230748
Formula: C20H12O2
MW: 284.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight284.3
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass284.083729621
Monoisotopic Mass284.083729621
Topological Polar Surface Area34.1 Ų
Heavy Atom Count22
Formal Charge0
Complexity535
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
A4538-25INCA-6
452285-01INCA 6
A15380-10INCA-6 10mg
A15380-5INCA-6 5mg
A15380-500INCA-6 500mg
A15380-100INCA-6 100mg
A15380-25INCA-6 25mg
A15380-50INCA-6 50mg
abx430242Protein INCA (INCA) Antibody
abx616103Protein INCA (INCA) Peptide

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