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PF-562271 hydrochloride

CAT: 0931-T21768-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T21768-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
939791-41-0
Target
PYK2, FAK, CDK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Purity
0.9852
Bioactivity
PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Smiles
Cl.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Molecular Formula
C21H20F3N7O3S HCl
Molecular Weight
543.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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