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(R) -Lisofylline

CAT: 0931-T21694-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T21694-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
100324-81-0
Target
STAT
Related Pathways
Stem Cells, JAK/STAT signaling
Purity
0.9985
Bioactivity
(R) -Lisofylline ((R) -Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 μM) that interrupts IL-12 signaling-mediated STAT4 activation, making it useful for studies on the treatment of type 1 diabetes and autoimmune disorders.
Smiles
C[C@@H](O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O
Molecular Formula
C13H20N4O3
Molecular Weight
280.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

100324-81-0

PubChem
cas100324-81-0
modify2026-05-17
description(R)-lisofylline is a 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus. It has a role as an immunomodulator and an anti-inflammatory agent. It is an enantiomer of a (S)-lisofylline.
synonyms
(R)-LisofyllineLISOFYLLINE100324-81-0ProTecLisophyllineCT-1501RlisofilinaCT 1501R(R)-LisophyllineLisofylline, (r)-+ 15 more
PubChem LinkClick here

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