PF-4981517

CAT: 0931-T21548-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T21548-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1390637-82-7
Target
Cytochromes P450
Related Pathways
Metabolism
Purity
0.9983
Bioactivity
PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4) . The IC 50 values for CYP3A activity are 0.03 ?M,17 ?M, and 71 ?M for CYP3A4, CYP3A5, and CYP3A7, respectively. PF-4981517 is able to be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug Metabolism.
Smiles
Cc1ccc(cc1)-c1c(cnn1C)-c1nn(C)c2ncnc(N3CC[C@@H](C3)N3CCCCC3)c12
Molecular Formula
C26H32N8
Molecular Weight
456.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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