PF-4981517

• Target :

  Cytochromes P450

• Related Pathways :

  Metabolism

• Purity :

  0.9983

• Bioactivity :

  PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4) . The IC 50 values for CYP3A activity are 0.03 ?M,17 ?M, and 71 ?M for CYP3A4, CYP3A5, and CYP3A7, respectively. PF-4981517 is able to be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug Metabolism.

• Smiles :

  Cc1ccc(cc1)-c1c(cnn1C)-c1nn(C)c2ncnc(N3CC[C@@H](C3)N3CCCCC3)c12

• Molecular Formula :

  C26H32N8

• Molecular Weight :

  456.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1390637-82-7