Phleomycin

• Target:

  Antibiotic|||Antibacterial|||DNA/RNA Synthesis

• Related Pathways:

  Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair

• Bioactivity:

  Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.

• Smiles:

  NC1=NC(C(NCC(N)C(N)=O)CC(N)=N)=NC(C(NC(C(O[C@@]2(OC3[C@H](O)[C@@](O)(C(N)=O)[C@@H](O)C(CO)O3)[C@H](C)[C@@H](O)[C@H](O)[C@H](CO)O2)C4=CNC=N4)C(C(O)C(C)C(NC(C(C)=O)C(NCCC5=NC(C6=NC(C(N)=O)=CS6)CS5)=O)=O)=O)=O)=C1

• Molecular Formula:

  C48H69N17O20S2

• Molecular Weight:

  1268.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  11006-33-0