Aloisine A

CAT: 0931-MF-0065291-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0065291-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
496864-16-5
Target
Others|||ERK|||GSK-3|||JNK|||CDK|||CFTR
Related Pathways
Stem Cells|||Cell Cycle/Checkpoint|||MAPK|||Membrane transporter/Ion channel|||PI3K/Akt/mTOR signaling|||Others
Bioactivity
Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3? (IC50: 500nM), GSK-3? (IC50: 650nM), JNK (IC50~3-10?M) .
Smiles
C(CCC)C1=C(NC=2C1=NC=CN2)C3=CC=C(O)C=C3
Molecular Formula
C16H17N3O
Molecular Weight
267.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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