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LCL161

CAT: 0931-T2080-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T2080-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1005342-46-0
Target
IAP
Related Pathways
Apoptosis
Purity
0.9987
Bioactivity
LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP (IC50=35 nM) in HEK293 cells and also inhibits cIAP1 (IC50=0.4 nM) in MDA-MB-231 cells. LCL161 has potential antitumor activity.
Smiles
C([C@@H](NC([C@@H](NC)C)=O)[C@H]1CCCCC1)(=O)N2[C@@H](CCC2)C3=NC(C(=O)C4=CC=C(F)C=C4)=CS3
Molecular Formula
C26H33FN4O3S
Molecular Weight
500.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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