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JANEX-1

CAT: 0931-T2045-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T2045-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
202475-60-3
Target
JAK
Related Pathways
Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Angiogenesis
Purity
0.9981
Bioactivity
JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM) ; little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases.
Smiles
COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC
Molecular Formula
C16H15N3O3
Molecular Weight
297.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C