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MLN9708 analogues

CAT: 0931-T2016-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T2016-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1201902-80-8
Target
Proteasome, Autophagy
Related Pathways
Autophagy, Proteases/Proteasome, Ubiquitination
Purity
0.9923
Bioactivity
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (Ki50=0.93 nM, IC50=3.4 nM/) . The biologically active form of MLN9708 (Ixazomib Citrate) is MLN2238 in aqueous solutions or plasma.
Smiles
CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O
Molecular Formula
C20H23BCl2N2O9
Molecular Weight
517.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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