Imipramine

CAT: 0931-T20025-02Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T20025-02Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

50-49-7

Target

Apoptosis, Autophagy, Serotonin Transporter

Related Pathways

Apoptosis, Autophagy, Neuroscience

Purity

0.994

Bioactivity

Imipramine (Dimipressin) is an orally active Fascin1 inhibitor with antidepressant and antitumor activity.Imipramine inhibits the 5-hydroxytryptamine transporter (IC50: 32 nM), induces apoptosis, and induces autophagy in U-87MG glioma cells.Imipramine has neuroprotective and immunomodulatory activities, inhibits TNT, and is used to label brain blood vessels.Imipramine is a neuroprotective and immunomodulatory compound. Imipramine has neuroprotective and immunomodulatory activities, inhibits invasion and migration of TNBC cells, and can be used to study breast cancer and epilepsy.

Smiles

C=1C=CC2=C(C1)N(C=3C=CC=CC3CC2)CCCN(C)C

Molecular Formula

C19H24N2

Molecular Weight

280.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Imipramine

Imipramine is a dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom. It has a role as an antidepressant, an adrenergic uptake inhibitor and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It derives from a hydride of a 5H-dibenzo[b,f]azepine.

CAS Number	50-49-7
PubChem CID	3696
IUPAC Name	3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Molecular Formula	C19H24N2
Molecular Weight	280.4
XLogP	4.8
Topological Polar Surface Area	6.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Heavy Atom Count	21
Formal Charge	0
Complexity	291

SMILES

CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31

InChI

InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3

InChIKey

BCGWQEUPMDMJNV-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 50-49-7

CID: 3696

Formula: C19H24N2

MW: 280.4

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	280.4
XLogP3	4.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	280.193948774
Monoisotopic Mass	280.193948774
Topological Polar Surface Area	6.5 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	291
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BA2970-50	Imipramine
20-1519	Imipramine antibody
CS-EL-00111	Imipramine-d3
KAA07524-01	Imipramine pamoate
I7250-02	Imipramine discontinued
014783	Imipramine-d6
MBS385478-01	Imipramine Hydrochloride
MBS6125869-01	Imipramine (PE)
MBS3611107-01	Imipramine (hydrochloride)
MBS310868-01	MAb to Imipramine

Imipramine

Chemical Information

Alternative Products

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