Fedratinib

• Target:

  JAK|||FLT|||Apoptosis|||c-RET

• Related Pathways:

  JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||Apoptosis

• Purity:

  0.9996

• Bioactivity:

  Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.

• Smiles:

  Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C

• Molecular Formula:

  C27H36N6O3S

• Molecular Weight:

  524.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  936091-26-8