Mertansine

• Target:

  ADC Cytotoxin|||Microtubule Associated

• Related Pathways:

  Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

• Purity:

  >99.99%

• Bioactivity:

  Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.

• Smiles:

  CO[C@@H]1\C=C/C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCS)[C@@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2

• Molecular Formula:

  C35H48ClN3O10S

• Molecular Weight:

  738.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  139504-50-0