CKI-7

• Target:

  ROCK|||Casein Kinase|||SGK|||S6 Kinase|||CDK

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Stem Cells|||Metabolism|||Cytoskeletal Signaling|||MAPK|||Cell Cycle/Checkpoint

• Purity:

  >99.99%

• Bioactivity:

  CKI-7 is a potent, ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 ?M; Ki: 8.5 ?M) and a selective Cdc7 kinase inhibitor. It also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.

• Smiles:

  Cl.Cl.NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

• Molecular Formula:

  C11H14Cl3N3O2S

• Molecular Weight:

  358.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1177141-67-1