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AZ31

CAT: 0931-T19671-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T19671-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2088113-98-6
Target
ATM/ATR
Related Pathways
PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Purity
0.981
Bioactivity
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
Smiles
N([C@@H](C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4
Molecular Formula
C24H28N4O3
Molecular Weight
420.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T4443-01AZ32

Alternative Products

CatalogName
BA3716-10AZ31
A16813-50AZ31 50mg
A16813-2AZ31 2mg
A16813-25AZ31 25mg
A16813-10AZ31 10mg
A16813-5AZ31 5mg
A16813-10mM-DAZ31 10mM * 1mL in DMSO

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