AZ31

CAT: 0931-MF-0013607-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013607-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2088113-98-6
Target
ATM/ATR
Related Pathways
PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Purity
0.981
Bioactivity
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
Smiles
N([C@@H](C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4
Molecular Formula
C24H28N4O3
Molecular Weight
420.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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