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PD 109488

CAT: 0931-T19631-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T19631-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
103733-49-9
Target
Others, Drug Metabolite
Related Pathways
Others, Metabolism
Bioactivity
PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling.
Smiles
[C@@H](C(OCC)=O)(CCC1=CC=CC=C1)N2C(=O)[C@]3(N(C(=O)[C@@H]2C)CC=4C(C3)=CC=CC4)[H]
Molecular Formula
C25H28N2O4
Molecular Weight
420.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C