PD 109488

• Target :

  Others|||Drug Metabolite

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling.

• Smiles :

  [C@@H](C(OCC)=O)(CCC1=CC=CC=C1)N2C(=O)[C@]3(N(C(=O)[C@@H]2C)CC=4C(C3)=CC=CC4)[H]

• Molecular Formula :

  C25H28N2O4

• Molecular Weight :

  420.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  103733-49-9