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Ciluprevir

CAT: 0931-T19627-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T19627-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
300832-84-2
Target
HCV Protease, Others
Related Pathways
Microbiology/Virology, Proteases/Proteasome, Others
Bioactivity
Ciluprevir is an effective and selective HCV NS3 protease inhibitor with proven antiviral effect in humans. Ciluprevir may be an antiviral agent for individuals infected with non-genotype-1 HCV. In vitro sensitivity studies with Ciluprevir showed a decrease in affinity for proteases of genotypes 2 and 3 (Ki: 80 to 90 nM) compared to genotype 1 enzymes (Ki: 1.5 nM) .
Smiles
C(O)(=O)[C@]12[C@@](C1)(/C=C/CCCCC[C@H](NC(OC3CCCC3)=O)C(=O)N4[C@](C(=O)N2)(C[C@@H](OC=5C6=C(N=C(C5)C=7N=C(NC(C)C)SC7)C=C(OC)C=C6)C4)[H])[H]
Molecular Formula
C40H50N6O8S
Molecular Weight
774.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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