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LOM612

CAT: 0931-T19405-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T19405-02Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2173232-79-4
Target
FOXO
Related Pathways
Apoptosis
Bioactivity
LOM612 is a potent and specific FOXO relocator that induces nuclear translocation of the FOXO3a reporter protein as well as endogenous FOXO3a and FOXO1 in a dose-dependent manner in U2OS cells, down-regulates the expression of c-Myc and cyclin D1, and has anti-proliferative effects in human cancer cell lines.
Smiles
O=C1C=2SN=C(C2C(=O)C=3C=CC=CC13)N(C)C
Molecular Formula
C13H10N2O2S
Molecular Weight
258.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

3-(Dimethylamino)benzo[f][1,2]benzothiazole-4,9-dione
CAS Number2173232-79-4
PubChem CID134821683
IUPAC Name3-(dimethylamino)benzo[f][1,2]benzothiazole-4,9-dione
Molecular FormulaC13H10N2O2S
Molecular Weight258.30
XLogP2.7
Topological Polar Surface Area78.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity385
SMILES
CN(C)C1=NSC2=C1C(=O)C3=CC=CC=C3C2=O
InChI
InChI=1S/C13H10N2O2S/c1-15(2)13-9-10(16)7-5-3-4-6-8(7)11(17)12(9)18-14-13/h3-6H,1-2H3
InChIKey
LMNFZYAIQJKFFX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(Dimethylamino)benzo[f][1,2]benzothiazole-4,9-dione
CAS: 2173232-79-4
CID: 134821683
Formula: C13H10N2O2S
MW: 258.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight258.30
XLogP32.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass258.04629874
Monoisotopic Mass258.04629874
Topological Polar Surface Area78.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA7726-5LOM612
A12343-50LOM612 50mg
A12343-10LOM612 10mg
HY-101035RLOM612 (Standard)
A12343-100LOM612 100mg
A12343-25LOM612 25mg
A12343-5LOM612 5mg
A12343-10mM-DLOM612 10mM * 1mL in DMSO

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