Filgotinib

• Target:

  HIV Protease|||JAK|||Tyrosine Kinases

• Related Pathways:

  Stem Cells|||JAK/STAT signaling|||Microbiology/Virology|||Angiogenesis|||Proteases/Proteasome|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

• Purity:

  0.9979

• Bioactivity:

  Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 values of 10 nM for JAK1, 28 nM for JAK2, 810 nM for JAK3, and 116 nM for TYK2.

• Smiles:

  O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1

• Molecular Formula:

  C21H23N5O3S

• Molecular Weight:

  425.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1206161-97-8