Anacetrapib

• Target:

  Others|||CETP

• Related Pathways:

  Others|||Metabolism

• Purity:

  0.9987

• Bioactivity:

  Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP (C13S) inhibitor (IC50: 7.9 nM and 11.8 nM) . Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.

• Smiles:

  COc1cc(F)c(cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C

• Molecular Formula:

  C30H25F10NO3

• Molecular Weight:

  637.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  875446-37-0