Anacetrapib

CAT: 0931-MF-0019980-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0019980-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
875446-37-0
Target
Others|||CETP
Related Pathways
Others|||Metabolism
Purity
0.9987
Bioactivity
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP (C13S) inhibitor (IC50: 7.9 nM and 11.8 nM) . Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.
Smiles
COc1cc(F)c(cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C
Molecular Formula
C30H25F10NO3
Molecular Weight
637.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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