VCP-Eribulin

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  VCP-Eribulin, an Eribulin-based drug for antibody conjugates[1], combines the VCP (ADCs linker) with Eribulin, a distinct microtubule inhibitor used in cancer treatments[2].

• Smiles:

  C=C1C[C@@H]2CC[C@@]34O[C@@H]5[C@]6([C@]([C@@](O3)([C@@](C4)(O6)[H])[H])(O[C@@]7([C@@]5(O[C@](CC7)(CC(=O)C[C@]8([C@@](O[C@H](C[C@@H](CNC(OCC9=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C9)=O)O)[C@@H]8OC)(C[C@H]%10O[C@@H](CC[C@@H]1O2)C[C@@H](C)C%10=C)[H])[H])[H])[H])[H])[H])[H]

• Molecular Formula:

  C59H86N6O16

• Molecular Weight:

  1135.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2130869-17-7