Thalidomide-O-PEG2-propargyl

• Target:

  Others|||Autophagy|||E3 Ligase Ligand-Linker Conjugate|||Apoptosis

• Related Pathways:

  PROTAC|||Autophagy|||Others|||Apoptosis

• Bioactivity:

  Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].

• Smiles:

  O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCOCCOCC#C)C3C2=O)CC1

• Molecular Formula:

  C20H20N2O7

• Molecular Weight:

  400.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2098487-52-4