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P7C3

CAT: 0931-T1880-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T1880-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
301353-96-8
Target
Others
Related Pathways
Others
Purity
0.996
Bioactivity
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, before neuronal cell death occurs, in a rodent model of blast-mediated traumatic brain injury (TBI) . This protective quality may be linked to the ability of P7C3 molecules to activate nicotinamide phosphoribosyltransferase, the rate-limiting enzyme in nicotinamide adenine dinucleotide salvage.
Smiles
OC(CNc1ccccc1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12
Molecular Formula
C21H18Br2N2O
Molecular Weight
474.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
B6028-5.1P7C3

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