Kobe0065

CAT: 0931-T1876-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T1876-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

436133-68-5

Target

Raf, Ras, Apoptosis

Related Pathways

GPCR/G Protein, Apoptosis, MAPK

Purity

>99.99%

Bioactivity

Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf interaction by structure-based drug design (SBDD) ; it displays potent activity, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.

Smiles

Cc1ccc(NC(=S)NNc2c(cc(cc2[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O)cc1Cl

Molecular Formula

C15H11ClF3N5O4S

Molecular Weight

449.79

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
C13331-10mg	Kobe0065
A13135-50	Kobe0065 50mg
A13135-500	Kobe0065 500mg
A13135-5	Kobe0065 5mg
A13135-200	Kobe0065 200mg
A13135-100	Kobe0065 100mg
A13135-25	Kobe0065 25mg

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