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SC-VC-PAB-DM1

CAT: 0931-T18678-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T18678-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2259318-47-1
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
SC-VC-PAB-DM1 is a drug-linker conjugate used in Antibody-Drug Conjugates (ADC), combining DM1 (Mertansine, a tubulin inhibitor) with the SC-VC-PAB[1] ADC linker to deliver potent antitumor activity.
Smiles
[H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(C\C(C)=C/C=C/[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)[C@H](C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCC(=O)ON2C(=O)CCC2=O)C(C)C)cc1 |c:17,t:19|
Molecular Formula
C61H82ClN9O19
Molecular Weight
1280.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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