DFKBP-1

CAT: 0931-T18597-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T18597-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1799711-22-0

Target

PROTACs, FKBP

Related Pathways

PROTAC, Apoptosis, Immunology/Inflammation, Autophagy

Bioactivity

DFKBP-1 is a potent PROTAC-based FKBP12 degrader incorporating the FKBP12 ligand SLF, the Thalidomide-based cereblon ligand, and a linker[1].

Smiles

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCNC(CCC(NC4=CC([C@H](OC(=O)[C@H]5N(C(C(C(CC)(C)C)=O)=O)CCCC5)CCC6=CC(OC)=C(OC)C=C6)=CC=C4)=O)=O)=O

Molecular Formula

C53H64N6O14

Molecular Weight

1009.11

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
GTR19225052-01	DFKBP-1
A23955-1	DFKBP-1 1mg
A23955-5	DFKBP-1 5mg
A23955-50	DFKBP-1 50mg
A23955-10	DFKBP-1 10mg
OF59775-01	1,1,1,1,1-Kestoheptaose
N2864-5.1	1,1,1,1-Kestohexaose
112040	1,1,1,1-Kestohexose
410417-01	1,1,1-Trichloromethanesulfonic Acid 1,1'-Anhydride