PC Mal-NHS carbonate ester

CAT: 0931-MF-0043127-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0043127-01Size:100 mg
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CAS Number
1408057-91-9
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs) [1]. This chemical compound facilitates drug-antibody conjugation, enabling targeted delivery and enhanced therapeutic efficacy. Its unique carbonate ester structure allows efficient cleavage in the targeted environment, ensuring controlled drug payload release, highlighting its significance in innovative and targeted cancer therapies.
Smiles
O=C(ON1C(=O)CCC1=O)OC(C2=CC(OC)=C(OCCCC(=O)NCCN3C(=O)C=CC3=O)C=C2N(=O)=O)C
Molecular Formula
C24H26N4O12
Molecular Weight
562.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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