PC Mal-NHS carbonate ester

• Target:

  ADC Linker

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs) [1]. This chemical compound facilitates drug-antibody conjugation, enabling targeted delivery and enhanced therapeutic efficacy. Its unique carbonate ester structure allows efficient cleavage in the targeted environment, ensuring controlled drug payload release, highlighting its significance in innovative and targeted cancer therapies.

• Smiles:

  O=C(ON1C(=O)CCC1=O)OC(C2=CC(OC)=C(OCCCC(=O)NCCN3C(=O)C=CC3=O)C=C2N(=O)=O)C

• Molecular Formula:

  C24H26N4O12

• Molecular Weight:

  562.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1408057-91-9