Regorafenib

• CAS Number :

  755037-03-7

• Target :

  PDGFR|||c-Kit|||Tie-2|||Raf|||Autophagy|||FGFR|||VEGFR|||c-RET

• Related Pathways :

  Apoptosis|||Angiogenesis|||Tyrosine Kinase/Adaptors|||MAPK|||Autophagy

• Purity :

  0.9995

• Bioactivity :

  Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFR?, exhibiting both antitumor and anti-angiogenic activity.

• Smiles :

  CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1

• Molecular Formula :

  C21H15ClF4N4O3

• Molecular Weight :

  482.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C