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Obeticholic Acid

CAT: 0931-T1789-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T1789-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
459789-99-2
Target
Autophagy, FXR
Related Pathways
Metabolism, Autophagy
Purity
0.9997
Bioactivity
Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist with an EC50 of 99 nM and is able to upregulate IκB-α, KLF-2, and KLF-4 expression. Obeticholic Acid (6-ECDCA, INT-747) also shows potential for treating hepatic steatosis, inflammation, and fibrosis while increasing insulin sensitivity.
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CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12
Molecular Formula
C26H44O4
Molecular Weight
420.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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B1898-5Obeticholic Acid
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MBS5764603Glyco-Obeticholic acid
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