Canagliflozin

• Target:

  SGLT

• Related Pathways:

  GPCR/G Protein

• Purity:

  >99.99%

• Bioactivity:

  Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM) . Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM) .

• Smiles:

  O[C@H]1[C@@H] (O[C@H] (CO) [C@@H] (O) [C@@H]1O) C2=CC (CC=3SC (=CC3) C4=CC=C (F) C=C4) =C (C) C=C2

• Molecular Formula:

  C24H25FO5S

• Molecular Weight:

  444.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  842133-18-0