Canagliflozin

• Target:

  SGLT

• Related Pathways:

  GPCR/G Protein

• Purity:

  >99.99%

• Bioactivity:

  Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM) . Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM) .

• Smiles:

  O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC=3SC(=CC3)C4=CC=C(F)C=C4)=C(C)C=C2

• Molecular Formula:

  C24H25FO5S

• Molecular Weight:

  444.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  842133-18-0