Canagliflozin

• CAS Number :

  842133-18-0

• Target :

  SGLT

• Related Pathways :

  GPCR/G Protein

• Purity :

  >99.99%

• Bioactivity :

  Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM) . Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM) .

• Smiles :

  O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC=3SC(=CC3)C4=CC=C(F)C=C4)=C(C)C=C2

• Molecular Formula :

  C24H25FO5S

• Molecular Weight :

  444.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C