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ATP-polyamine-biotin

CAT: 0931-T17454-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T17454-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1800401-93-7
Target
Others
Related Pathways
Others
Bioactivity
ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. ATP-polyamine-biotin is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker.
Smiles
O[C@H]1[C@](N2C=3C(N=C2)=C(N)N=CN3)(O[C@H](COP(OP(OP(NCCCN(CCCCN(CCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)C)C)(=O)O)(=O)O)(=O)O)[C@H]1O)[H]
Molecular Formula
C32H58N11O14P3S
Molecular Weight
945.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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