ATP-polyamine-biotin

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. ATP-polyamine-biotin is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker.

• Smiles :

  O[C@H]1[C@](N2C=3C(N=C2)=C(N)N=CN3)(O[C@H](COP(OP(OP(NCCCN(CCCCN(CCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)C)C)(=O)O)(=O)O)(=O)O)[C@H]1O)[H]

• Molecular Formula :

  C32H58N11O14P3S

• Molecular Weight :

  945.86

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1800401-93-7