Ala-Ala-Asn-PAB

CAT: 0931-T17365-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T17365-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2149584-00-7

Target

Others, ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related, Others

Purity

0.9731

Bioactivity

Ala-Ala-Asn-PAB is a cleavable peptide linker employed in antibody-drug conjugates (ADCs), improving the physicochemical properties and toxicity profiles of cytotoxic drugs by forming stable peptide-drug conjugates, and facilitating controlled drug release in targeted therapies.

Smiles

[C@H](C(NC1=CC=C(CO)C=C1)=O)(NC([C@@H](NC([C@H](C)N)=O)C)=O)CC(N)=O

Molecular Formula

C17H25N5O5

Molecular Weight

379.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Ala-Ala-Asn-PAB

CAS Number	2149584-00-7
PubChem CID	118966102
IUPAC Name	(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-N-[4-(hydroxymethyl)phenyl]butanediamide
Molecular Formula	C17H25N5O5
Molecular Weight	379.4
XLogP	-2.3
Topological Polar Surface Area	177
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Heavy Atom Count	27
Formal Charge	0
Complexity	548

SMILES

C[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N

InChI

InChI=1S/C17H25N5O5/c1-9(18)15(25)20-10(2)16(26)22-13(7-14(19)24)17(27)21-12-5-3-11(8-23)4-6-12/h3-6,9-10,13,23H,7-8,18H2,1-2H3,(H2,19,24)(H,20,25)(H,21,27)(H,22,26)/t9-,10-,13-/m0/s1

InChIKey

VPXFRPRRAXTBSH-KWBADKCTSA-N

Chemical Structure

2D Structure

CAS: 2149584-00-7

CID: 118966102

Formula: C17H25N5O5

MW: 379.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	379.4
XLogP3	-2.3
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	379.18556891
Monoisotopic Mass	379.18556891
Topological Polar Surface Area	177 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	548
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T30274-01	Azido-PEG4-Ala-Ala-Asn (Trt) -PAB
T15329-01	Fmoc-PEG3-Ala-Ala-Asn (Trt) -PAB
T31835-01	Fmoc-PEG3-Ala-Ala-Asn (Trt) -PAB-PNP
T38984-01	Z-Ala-Ala-Asn-AMC
T17945-01	Fmoc-Ala-Ala-Asn-PABC-PNP
T87826-01	NHS-Ala-Ala-Asn-active metabolite
T17946-01	Fmoc-Ala-Ala-Asn (Trt) -OH
T87729-01	Fmoc-Ala-Ala-PAB
T87780-01	MP-Ala-Ala-PAB
T87757-01	MC-Ala-Ala-PAB

Alternative Products

Catalog	Name
MBS133212	Ala-Ala-Asn-PAB
BIPG2118-01	Fmoc-Ala-Ala-Asn-PAB
HY-139245-01	MC-Ala-Ala-Asn-PAB
GTR19234492-01	Ala-Ala-Asn-PAB TFA
HY-129360A	Ala-Ala-Asn-PAB (TFA)
MBS5768544	Azido-PEG5-Ala-Ala-Asn-PAB
OR1038487	Fmoc-PEG4-Ala-Ala-Asn-PAB
GTR19216147-01	Mal-propyl-Ala-Ala-Asn-PAB
HY-148031	MC-Ala-Ala-Asn-PAB-PNP
GTR19154245-01	MC-Ala-Ala-Asn (Trt) -PAB

Ala-Ala-Asn-PAB

Chemical Information

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