9-Decyn-1-ol

• Target:

  PROTAC Linker|||Others

• Related Pathways:

  Others|||PROTAC

• Bioactivity:

  9-Decyn-1-ol is an alkyl/ether-based PROTAC linker used in synthesizing PROTACs, acting as a conjugation agent to combine GDC-0068 and Lenalidomide to form INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].

• Smiles:

  C(CCCC#C)CCCCO

• Molecular Formula:

  C10H18O

• Molecular Weight:

  154.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  17643-36-6