(-) -Indolactam V

• Target:

  PKC

• Related Pathways:

  Chromatin/Epigenetic|||Cytoskeletal Signaling

• Bioactivity:

  (-) -Indolactam V, a potent PKC activator, exhibits binding affinities (Kis) of 3.36 nM and 1.03 ?M for ?-CRD2 and ?-CRD2, respectively, and dissociation constants (Kds) of 5.5 nM (?-C1B), 7.7 nM (?-C1B), 8.3 nM (?-C1B), 18.9 nM (?-C1A-long), 20.8 nM (?-C1A-long), 137 nM (?-C1B), 138 nM (?-C1A), and 213 nM (?-C1B), also demonstrating antitumor activity.

• Smiles:

  CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23

• Molecular Formula:

  C17H23N3O2

• Molecular Weight:

  301.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  90365-57-4