VZ185

• Target:

  Epigenetic Reader Domain|||PROTACs

• Related Pathways:

  PROTAC|||Chromatin/Epigenetic

• Bioactivity:

  VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively) .

• Smiles:

  CN1C=C (C=2C (C1=O) =CN=CC2) C3=CC (OC) =C (CN4CCN (CCCCCOC5=C (CNC (=O) [C@H]6N (C ([C@@H] (NC (=O) C7 (F) CC7) C (C) (C) C) =O) C[C@H] (O) C6) C=CC (=C5) C=8SC=NC8C) CC4) C (OC) =C3

• Molecular Formula:

  C53H67FN8O8S

• Molecular Weight:

  995.21

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2306193-61-1