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VU0467485

CAT: 0931-T17245Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T17245Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1451994-10-7
Target
AChR, Others
Related Pathways
Others, Neuroscience
Bioactivity
VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6 nM and 78.8 nM at the rat and human M4 receptors, respectively) . VU0467485 displays selectivity for M4 over human and rat M1/2/3/5.
Smiles
COc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1F
Molecular Formula
C17H17FN4O2S
Molecular Weight
360.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-120184-01VU0467485
MBS5783323O-Desmethyl VU0467485

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