PF-06737007

• Target :

  Trk receptor

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively) .

• Smiles :

  O(C1=C(C(N)=O)C=CC(OCC(C)(C)O)=C1)[C@@H]2[C@H](F)CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC2

• Molecular Formula :

  C25H28F4N2O6

• Molecular Weight :

  528.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1863905-38-7