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Trabectedin

CAT: 0931-T17155-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T17155-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
114899-77-3
Target
Apoptosis, Reactive Oxygen Species
Related Pathways
Apoptosis, Immunology/Inflammation, NF-κB, Metabolism
Purity
≥98%
Bioactivity
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0.1 nM, 1.5 nM and 3.7 nM, respectively.
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[H][C@@]12[C@@H]3SC[C@]4(NCCc5cc(O)c(OC)cc45)C(=O)OC[C@H](N1[C@@H](O)[C@@H]1Cc4cc(C)c(OC)c(O)c4[C@H]2N1C)c1c2OCOc2c(C)c(OC(C)=O)c31
Molecular Formula
C39H43N3O11S
Molecular Weight
761.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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