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Tos-PEG4-t-butyl ester

CAT: 0931-T17133-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T17133-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
217817-01-1
Target
Others, PROTAC Linker
Related Pathways
PROTAC, Others
Bioactivity
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2/FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].
Smiles
S(OCCOCCOCCOCCC(OC(C)(C)C)=O)(=O)(=O)C1=CC=C(C)C=C1
Molecular Formula
C20H32O8S
Molecular Weight
432.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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