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TMC310911

CAT: 0931-T17106-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T17106-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1000287-05-7
Target
HIV Protease, Others
Related Pathways
Microbiology/Virology, Proteases/Proteasome, Others
Bioactivity
TMC310911 is an effective and orally active HIV type-1 protease inhibitor (EC50: ranged from 2.2 nM to 14.2 nM for wild-type HIV-1) . TMC310911 has effective activity against a wide spectrum of recombinant HIV-1 isolates.
Smiles
[H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc2nc(NC3CCN(CC3)C3CCCC3)sc2c1
Molecular Formula
C38H53N5O7S2
Molecular Weight
755.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

1000287-05-7

PubChem
cas1000287-05-7
modify2026-05-17
descriptionTMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available [darunavir]. It is being investigated for use in HIV-1 infections. TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, making it a potentially desirable therapy for both treatment-naive and PI-experienced patients. TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.
synonyms
1000287-05-7TMC310911TMC-310911ASC090151W500HPASC 09DTXSID001028122
Carbamic acid, N-((1S,2R)-3-(((2-((1-cyclopentyl-4-piperidinyl)amino)-6-benzothiazolyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3R,3aS,6aR)-hexahydrofuro(2,3-b)furan-3-yl ester
(3R,3aS,6aR)-Hexahydrofuro(2,3-b)furan-3-yl N-((1S,2R)-3-(((2-((1-cyclopentyl-4-piperidinyl)amino)-6-benzothiazolyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamate
RefChem:898522+ 15 more
PubChem LinkClick here

Alternative Products

CatalogName
BA1978-25TMC310911

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