TAS6417

• CAS Number :

  1661854-97-2

• Target :

  Apoptosis|||EGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Apoptosis

• Purity :

  0.9971

• Bioactivity :

  Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor that uniquely binds to the ATP binding site of the EGFR hinge region with an IC50 value of 1.1-8.0 nM.

• Smiles :

  CC1=C[C@@H](Cn2c1c(-c1cnc3ccccc3c1)c1c(N)ncnc21)NC(=O)C=C

• Molecular Formula :

  C23H20N6O

• Molecular Weight :

  396.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C