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Streptonigrin

CAT: 0931-T16946-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16946-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3930-19-6
Target
Others, PAD, MDM-2/p53, HIF/HIF Prolyl-Hydroxylase, Apoptosis, E1/E2/E3 Enzyme, Antibiotic
Related Pathways
Chromatin/Epigenetic, Apoptosis, Microbiology/Virology, Metabolism, Others, Ubiquitination
Bioactivity
Streptonigrin is a natural product produced by Streptomyces flocculus, has both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor (IC50s: 48.3±34.2 μM, 26.1±0.3 μM, 0.43±0.03 μM, and 2.5±0.4 μM for PAD1, PAD2, PAD3, and PAD4, respectively) .
Smiles
COC1=C(N)C(=O)c2nc(ccc2C1=O)-c1nc(C(O)=O)c(C)c(c1N)-c1ccc(OC)c(OC)c1O
Molecular Formula
C25H22N4O8
Molecular Weight
506.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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