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SAFit2

CAT: 0931-T16836-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16836-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1643125-33-0
Target
FKBP
Related Pathways
Autophagy, Immunology/Inflammation, Apoptosis
Purity
>99.99%
Bioactivity
SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51) with a Ki value of 6 nM. SAFit2 can enhance the binding of AKT2-AS160 and participate in the downstream response of glucocorticoid release in vivo. It is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.
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COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C2CCCCC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCCN3CCOCC3)c2)cc1OC
Molecular Formula
C46H62N2O10
Molecular Weight
802.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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