RTS-V5

• Target:

  Proteasome|||HDAC

• Related Pathways:

  Ubiquitination|||DNA Damage/DNA Repair|||Proteases/Proteasome|||Chromatin/Epigenetic

• Bioactivity:

  RTS-V5 is a dual inhibitor of HDAC/proteasome (IC50s: 6.9, 18, 15, 0.27, 0.53 ?M for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively) .

• Smiles:

  [C@@H](NC(=O)C1=CC=C(C(NO)=O)C=C1)(C(N[C@H](C(NCC2=CC=CC=C2)=O)C)=O)CC(NCC(C)(C)C)=O

• Molecular Formula:

  C27H35N5O6

• Molecular Weight:

  525.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2285346-31-6