RegisterLogin

Rigosertib

CAT: 0931-T16750-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0931-T16750-01Size:50 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
592542-59-1
Target
PI3K|||PLK|||FLT|||Apoptosis|||PDGFR|||Src|||CDK|||Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Apoptosis|||Angiogenesis|||Cytoskeletal Signaling
Purity
0.9953
Bioactivity
Rigosertib (ON-01910) is a selective, non-ATP-competitive PLK1 inhibitor (IC50: 9 nM) and multi-kinase inhibitor. As a selective anti-cancer agent, Rigosertib induces apoptosis by inhibiting the PI3 kinase/Akt pathway, promotes histone H2AX phosphorylation, and induces G2/M arrest in the cell cycle.
Smiles
C(=C/S(CC1=CC(NCC(O)=O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC
Molecular Formula
C21H25NO8S
Molecular Weight
451.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName

Alternative Products

CatalogName
BUP16324-01Rigosertib
MBS385857-01ON-01910 (rigosertib)
TRC-R590714-100MGRigosertib-d6
MBS130460-01Rigosertib (ON-01910)
202080Rigosertib sodium
A21868-2Rigosertib 2mg
HY-12037-01Rigosertib (sodium)
A21868-50Rigosertib 50mg
A21868-5Rigosertib 5mg
A21868-10Rigosertib 10mg

Popular Products