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Rhosin

CAT: 0931-T16746-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16746-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1173671-63-0
Target
Apoptosis, Rho, Ras
Related Pathways
GPCR/G Protein, Apoptosis, Cell Cycle/Checkpoint, MAPK
Bioactivity
Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM) . Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin causes cell apoptosis.
Smiles
C([C@H](C(N/N=C/C1=CC2=C(C=C1)N=CC=N2)=O)N)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C20H18N6O
Molecular Weight
358.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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