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Remibrutinib

CAT: 0931-T16730-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16730-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1787294-07-8
Target
BTK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9981
Bioactivity
Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM) . Remibrutinib has the potential for Chronic urticaria (CU) treatment.
Smiles
CN(CCOc1c(N)ncnc1-c1cc(F)cc(NC(=O)c2ccc(cc2F)C2CC2)c1C)C(=O)C=C
Molecular Formula
C27H27F2N5O3
Molecular Weight
507.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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