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Pyr10

CAT: 0931-T16686-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T16686-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1315323-00-2
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.997
Bioactivity
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor that distinguishes between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1) /Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) and has an IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells.
Smiles
Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F
Molecular Formula
C18H13F6N3O2S
Molecular Weight
449.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
QCC32300-01Pyr10
A20786-25Pyr10 25mg
A20786-100Pyr10 100mg
A20786-50Pyr10 50mg
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A20786-5Pyr10 5mg
A20786-10mM-DPyr10 10mM * 1mL in DMSO
217850TRPC3 Channel Inhibitor III, Pyr10 (N- (4- (3,5-bis (trifluoromethyl) -1H-pyrazol-1-yl) phenyl) -4-methylbenzenesulfonamide)

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